CRISPR gRNA Innovations from Discovery to the Clinic

Accelerate your CRISPR research and therapeutic development—from custom synthesis through rigorous analytics to GMP manufacturing

24

September

  • 3PM London / 10AM New York
  • Free
  • Why attend?
  • Speakers
  • Contact Us

Why attend?

The promise of CRISPR-based therapies hinges on the precision, purity, and performance of guide RNAs (gRNAs). Low-quality or impure gRNAs can reduce editing accuracy, increase off-target effects, and undermine the success of cell and gene therapies. As programs progress toward clinical translation, maintaining gRNA quality becomes even more critical. Ensuring gRNA quality across research, preclinical, and GMP stages demands tight process control, validated analytical methods, and adherence to regulatory expectations. Gaps in any of these areas can lead to product inconsistency and increased clinical risk. In this evolving landscape, choosing the right gRNA supplier is a critical step toward ensuring clinical success.

TriLink BioTechnologies invites you to learn from two experts helping to shape the future of CRISPR-based therapeutics. Dr. Cody Palumbo brings extensive experience in CRISPR development from the biotech and pharma industries, while Dr. Ortega leads analytical innovation for complex RNA products.

In this session, they’ll explore how you can:

  • Improve lead identification using high-purity gRNAs
  • Apply advanced methods to verify gRNA quality
  • Prepare your workflows for GMP manufacturing

 

Don’t miss this opportunity to level up your CRISPR programs with expert insights and practical takeaways. Register now to secure your spot and take the next step toward confident, clinic-ready gene editing.

Learning  Objectives of this webinar:

  1.  Understand how screening and lead candidate selection are enhanced with high-purity gRNAs
  2. Identify methods to ensure gRNA quality with advanced analytical characterization
  3. Gain practical insights to de-risk and simplify the transition to GMP manufacturing
  4. Explore comprehensive gene editing solutions from TriLink

 

Speakers

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Cody Palumbo, PhD
Senior Application Scientist, Tech Design

Dr. Cody Palumbo is a Senior Application Scientist in Technical Design at TriLink BioTechnologies, where he partners with customers to support gRNA, oligonucleotide, and gene editing workflows by providing technical guidance and customized solutions. He brings deep expertise in CRISPR-based technologies and therapeutic development, drawing on years of experience across biotech and pharmaceutical settings. Prior to TriLink, Dr. Palumbo served as Associate Director of Gene Editing Process Development and Tech Transfer at Sana Biotechnology and led a team of Process Development scientists at Bristol Myers Squibb focused on gene editing tools for cell therapies. He holds a Ph.D. in Chemistry from the University of California, Davis. Dr. Palumbo is passionate about bridging technical innovation with real-world impact and frequently speaks on the evolving landscape of genome editing technologies.

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Camila Ortega Ramirez, Ph.D.
Associate Director of Analytical Services

Dr. Ortega holds a doctorate in Molecular Biology and Analytical Chemistry from the University of Hawaii at Manoa. With a strong background in mass spectrometry, she serves as the Associate Director of Analytical Services at TriLink Biotechnologies. As part of the Analytical Development team, Dr. Ortega specializes in the physicochemical analysis of mRNA, oligonucleotides (i.e. gRNA), and small molecules such as NTPs and CleanCap® analogs. Her commitment to analytical excellence, combined with her scientific expertise, drives the development of robust methodologies to effectively fulfill client analytical requests and expand TriLink’s portfolio of analytical testing services.

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