Dr Shamsi will explore the evolution of oncology imaging, the limitations of RECIST 1.1, and how additional measurements can enhance early-phase decision-making and late-phase efficacy confirmation in clinical trials.
- The evolution of oncology clinical trials since RECIST 1.1
- The impact of immunotherapies, cell therapies, cancer vaccines, and ADCs
- RECIST Plus – enhanced features that integrate volumetric and radiological parameters for a more comprehensive analysis
The need for broad representation: The importance of ensuring that clinical trials include a wide range of patient populations to improve the applicability and validity of results across all demographic groups. This approach helps reflect real-world conditions and ensures treatments are safe and effective for everyone.
Patient-centric trial design: Focusing on designing trials with a patient-first approach, considering their needs, preferences, and challenges to improve engagement and outcomes
Inclusive trial design: Exploring strategies for creating accessible trials, such as flexible locations, culturally sensitive recruitment, and remote monitoring, to ensure participation from diverse groups.
Intersectionality and health outcomes: Examining how diversity, patient-centric approaches, and inclusive design intersect to improve trial relevance, reduce healthcare disparities, and enhance the generalizability of results.
Interactive roundtable sessions offer a unique opportunity to come together with your peers to share best practice and develop solutions to critical challenges facing the industry as a whole. Each discussion will be led by a table moderator and will focus on a different challenge within oncology clinical trials. Roundtables are an exciting, interactive way to build your personal network and learn from the experience and expertise of others.
After 30 minutes, delegates will have the opportunity to swap and choose a different table, and each roundtable will run twice.
- Roundtable 1: Measuring success by assessing the effectiveness of your patient enrollment strategy
Hosted by Irene Soto, Clinical Operations Expert
- Roundtable 2: Advantages and challenges of conducting multi-regional clinical trials in oncology
Hosted by Deepa Arora, Director, AJNA Therapeutics
- Roundtable 3: Fine-tuning the site-sponsor partnership
Hosted by Cecilia Tran Muchowski, Senior Director, Site Alliances, Genmab
- Roundtable 4: Bringing innovation to clinical trials
Hosted by Bobby Asem, Associate Director, ClinOps, Bluejay Therapeutics